LC & LC-MS Series

HPLC and UHPLC Troubleshooting: A Performance Qualification Approach

This course teaches a practical, performance-qualification approach to troubleshooting, helping you quickly identify and resolve issues across your HPLC and UHPLC systems. You’ll learn core operating principles, targeted maintenance techniques, and proven problem-solving strategies that prevent costly failures and keep your methods running reliably.
Two scientists setting up samples for HPLC analysis | Course graphic for "HPLC and UHPLC Troubleshooting" from Analytical Training

  • Solo or Team

    Subscriptions Available
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  • 7+ Hours

    of Video Content

    Learners

    Quizzes

    Modules

    Videos
    LC & LC-MS Series

    Course Description

    “HPLC & UHPLC Troubleshooting: A Performance Qualification Approach” is an intensive online course that teaches you the ins and outs of solving problems that occur with your high-performance liquid chromatography (HPLC) and ultra-high pressure liquid chromatography (UHPLC) methods.

    This is a unique web-based class. For convenient access and viewing, the course is split into seven major sections, and each of these sections is broken down into 3-6 modules, ranging from 8 to 28 min, with an average running time of 18 min.
    LC & LC-MS Series

    Course Highlights

    • The operating principles of each module in an HPLC and UHPLC system

    • A review of basic HPLC theory as it applies to troubleshooting and instrument maintenance

    • Why performance qualification (PQ) is so important to ensure the reliable operation of your HPLC and UHPLC and improve the quality of your results

    • Proven techniques for systematic problem-solving and instrument maintenance

    • The most effective, timesaving, money-saving approaches to preventing common hardware problems and method failures.

    About the instructor

    John Dolan

    John Dolan is considered to be the one of the world’s experts in HPLC. He has written more than 300 user-oriented articles on HPLC troubleshooting over the last 30 years in addition to more than 100 peer-reviewed technical articles on HPLC and related techniques. 
    His three books (co-authored with Lloyd Snyder), Troubleshooting HPLC Systems, Introduction to Modern Liquid Chromatography (3rd edn), and High-Performance Gradient Elution, are standard references on thousands of desks around the world. He has taught HPLC training classes around the world to more than 10,000 students.

    Preview This Course for Free

    Experience the first module before enrolling.
    Click the video activity in the first module below to get started—no purchase required.